Gas Chromatography (GC) has become indispensable in modern industries, as it not only provides accurate and reliable data but also offers real-time or near real-time results. This comprehensive course covers all aspects of GC, equipping both professionals and novices with the knowledge necessary to operate, maintain, and interpret GC results effectively.

Course Objectives:

By the end of the training, participants will be able to:

To build extensive understanding and excellent skills in gas chromatography technology and associated techniques used.
To operate the gas chromatography equipment in the safest and best practical way.
To build up the knowledge and skills on how to maintain gas chromatography and able to train others, particularly the graduates and newcomers.
To calibrate gas chromatography and produce results with the highest precision and accuracy and reliable source
To manage to troubleshoot and identify the source of the problem and the scientific method of eliminating the problem from reoccurring
To develop new methods and procedures development for new tests and using them in research and development projects
Be familiar with sampling and sample handling concepts, the effect of sampling error on overall precision, sample contamination and preservation, disposal of completed sample and reporting of data and sample accountability
Learn sample preparation, sample requirements for gases, liquids and solid, sample clean up, solvent, soxhlet, solid phase, and solid microextraction, sample derivatization, improved volatility and separation, improved sensitivity, and selectivity.
Differentiate packed versus capillary columns, the chromatographic process, and component separation, now the effects of carrier gas velocity, capillary tubing, sources of activity and structural flaws, silanol deactivation and column coating
Heighten their knowledge about capillary columns, its stationary phase, polarity and selectivity, the types of stationary phase and gas-solid adsorption columns
Gain knowledge on gas chromatographic separation effects, the effect of column length and diameter, stationary phase film thickness and stationary phase diffusivity, and also the effect of temperature and temperature programming on column flow, average linear velocity, solute retention, and chromatographic efficiency
Identify sample injection, learn the factors affecting injection bandwidth, split/splitless injectors, hot vaporizing injection, large volume injection, purge, and trap sampling also headspace and purge and trap sampling
Understand general aspects of GC detectors, like thermal conductivity detector, flame ionization, electron capture, thermionic, photoionization, flame photometric and chemiluminescent detectors
Recognize GC/MS capillary columns, ionization sources, mass analyzers, mass fragment detection, total ion chromatograms, and selective ion monitoring
Explain high-speed GC
Conduct validation of GC Methods, Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ)
Perform troubleshooting and applications

Who Should Attend?

This course is offering everything the professional and the novice needs to know about running, maintaining, and interpreting the results from Gas Chromatography. Analytical chemists, technicians, and scientists in allied disciplines will regard this course as the best in gas chromatography. In addition to serving as an invaluable update for the experienced practitioner, this course provides the beginner with a solid understanding of gas chromatographic theory and basic techniques.

Course Outlines:

Operating Principles of LC/MS and GC/MS
Strategies for Data Interpretation - EI, CI, MS/MS, and Ion-Source CAD
Ionization Techniques - EI, CI, APCI, and ES, Inlet-System Interfacing for LC and GC
Quantization Using GC/MS and LC/MS
Instrument Maintenance
Experimental Design
Use of Computer Tools for Generation of and Dealing with LC/MS, GC/MS, and MS/MS Data
Sources for GC/MS and LC/MS Method Development
MS Requirements for Hyphenated Techniques
Consult with expert instructors about your analytical problems and challenges
Strategy for interpreting mass spectral data
Compounds are amenable to various MS techniques
Operating principles of ionization sources, mass analyzers, and detectors
Operating principles of sample inlet systems (direct-probe and GC and LC inlet) and associated vacuum systems
How to process data with a data system; appreciate various aspects of tuning and troubleshooting a mass spectrometer
Library searching on benchtop data systems and the use of other computer-aided mass spectral interpretation tools
Using a vast array of the latest in modern GC/MS and LC/MS instrumentation
Chromatography techniques
Gas Chromatography technique
Sample preparation
GC components
GC columns
GC detectors
GC carriers
Electronic devices connected to GC
Maintenance and calibration of the gas chromatographic instrument
Troubleshooting and their solutions
Interpretation of test results and analysis
GC Methods and processes development
Combination of gas chromatographic technique with other techniques
Basic instructions and advanced operating procedures
Interface and overlaps of mixed chemicals

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